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Ready to ShipThe enzyme superoxide dismutase 1 belongs to a family of metalloenzymes that catalyze or enhance the activity of metabolic processes. SOD1, in particular, works on the superoxide anion, one of the most prevalent reactive oxygen species resulting from aerobic metabolism.
The enzyme then helps transform the superoxide into smaller and less harmful compounds like hydrogen peroxide. That way, it's able to help reduce oxidative cell stress and, by extension, cell damage and death, especially in vulnerable neuronal cells.
Some types available are as follows:
This is a supplement form of SOD1 in which the enzyme is usually embedded in a liposomal delivery matrix for protection from the digestive environment. It's often in powder form for easy mixing into food, drinks, or supplements. SOD powder can mitigate against oxidative cell damage by neutralizing superoxide radicals and similar ROS. It typically finds application in nutritional supplements, functional foods, and cosmeceutical devices for skin health.
It is usually packaged into hard-shell or soft-shell capsules where it's often combined with other antioxidants such as vitamin E, vitamin C, and others. Because these antioxidants work synergistically with SOD1, they offer heightened protection against oxidative damage. It's primarily used in nutritional supplements targeting overall health and aging.
Injectable SOD1 formulations, often lyophilized powders that require reconstitution, are typically administered in combination with stabilizing excipients like mannitol and sucrose intended for pharmaceuticals. There are usually intracranial, subcutaneous, and intramuscular delivery routes, depending on the desired therapeutic effect and speed of action. Often used in clinical settings to combat oxidative stress associated with neurodegenerative diseases.
Superoxide dismutase is an enzyme ubiquitous in virtually all human cells, hence freely extractable from yeast and other sources for cosmetic purposes. In this context, they are typically encapsulated in liposomes or niosomes for enhanced skin permeability. Creams, serums, gels, and lotions are the most popular forms for wrinkle reduction, skin repair, and other benefits.
It's common for some buyers to notice that various superoxide dismutase 1 products come in different shapes and sizes. But it's paramount to ensure they're buying the correct enzyme SOD1 product, considering all the available options, from delivery forms and sources to purity and encapsulation technology and more. That's why it's crucial for wholesalers to choose suitable products themselves so they can offer them to their customers.
Some of the factors to consider when selecting SOD1 products are as follows:
While oral SOD products like powders and capsules are versified for general antioxidant support, SOD injections are typically reserved for medical applications and offer direct therapeutic intervention. Topical SOD formulations are rampant for localized skin care. Hence, choosing the right formulation should adequately reflect the target market's needs and preferences.
Most superoxide dismutase is derived from yeast, particularly S. cerevisiae, and plant sources like cantaloupe, and barley sprout, among others. However, yeast-derived SOD is considered more bioactive and potent compared to others. But regardless of source, potency or bioavailability can be improved through encapsulation and delivery technologies like liposomes that protect it from degradation in the digestive tract.
As SOD1 is a pharmaceutical-grade enzyme, it's imperative that only high-purity products, the most commonly available forms of which are >99% pure, be chosen to guarantee safety and effectiveness. Wholesalers should also look for products with quality certifications such as Good Manufacturing Practices compliant with FDA regulations, as well as third-party laboratory evaluations.
Buyers should consider the primary SOD product market demand. For instance, health-conscious individuals may tend to prefer oral SOD supplements for general wellness, while medical professionals may order injectables for therapeutic uses. Similarly, cosmetic products such as lotions containing superoxide dismutase for skin repair could be a growing market.
For example, the regulations governing the SOD supplement market can be significantly different by country and region. Therefore, wholesalers must ensure that any product they're purchasing complies with the laws in the countries where they plan to sell it. It's also crucial to keep updated on any impending changes to these regulations that could affect the products' marketability.
How enzyme SOD1 supplements are used and the products they are typically found in depend on various factors, including formulation type, intended use, and dosage requirements. But regardless of the factors, it's often recommended to observe guidelines provided by manufacturers and consult medical experts, especially when planning to take high doses or for extended periods. Also, the following typical usage of various SOD1 products is worth noting:
Superoxide dismutase for skin is usually found in topical creams and gels containing other active ingredients like growth factors, collagen, and hyaluronic acid, which help rejuvenate the skin and make it more appealing. But for optimal results, it's often recommended to apply the creams once or twice daily onto clean, dry skin. In addition, it's crucial to perform a patch test and avoid contact with the eyes and mouth and broken skin. Results usually become evident within 4 to 6 weeks.
SOD injections are typically administered under the supervision of qualified healthcare professionals. The dosages depend on several factors, including the medical condition, patient weight, and treatment response. Beyond therapeutic applications for oxidative stress and neurodegenerative conditions, refrain from self-injecting without medical guidance. It should be stored mostly in a freezer as ice will ruin it.
Oral SOD supplements, powders, and capsules are usually recommended to be taken daily for general health and skin care, preferably in the morning on an empty stomach. It's often paired with other antioxidants, such as vitamin C, to heighten the extent and speed of skin and overall health benefits. However, consult a healthcare provider to know about possible drug interactions, especially when on medications. Observe for any adverse reactions to the product and discontinue use when they arise.
Oral SOD powders are commonly integrated into functional foods like protein shakes and nutritional drinks, which are often consumed post-workout or as meal supplements. The dosage is usually pre-measured and mixed into food or drinks of choice before consumption. However, anything containing proteases should be avoided as they would digest the SOD enzyme.
The effectiveness and quality of superoxide dismutase 1 products are highly dependent on proper storage and transportation. Therefore, both manufacturers and wholesalers must conserve them via the outlined storage and transportation tips to maintain product integrity and ensure safety for end users:
For instance, most SOD products are sensitive to temperature changes, especially heat, which can significantly degrade the enzyme activity. On the other hand, freezing temperatures can adversely affect product formulations. Therefore, it's necessary to keep them within their recommended temperature ranges, typically between 2°C and 8°C for injectables and 15°C and 30°C for topical and oral formulations.
However, ambient temperatures can cause topical and oral SODs to break down, and freezing can render injectables like NVG SOD1 ineffective. So, as a solution, insulated containers, cold packs, and specialized packaging materials like vacuum-sealed pouches are ideal for maintaining a stable thermal environment throughout the transportation duration and process. Also, using airtight containers for powders and capsules and opaque containers for SOD creams is prudent in preventing exposure to air, light, and moisture.
Because SOD products are sensitive and fragile, especially during transportation, it's recommended to use caution during handling. That is, products should be labeled as "fragile," and personnel should be trained on proper handling to prevent undue exposure to temperature variations. Also, products should be securely packed to prevent movement and adequately fasten them to minimize vibration during transit.
Again, SOD products should be stored in warehouses that maintain stable humidity and temperature and are free from direct sunlight. Additionally, as with other pharmaceuticals and nutraceuticals, keep them in a first-in, first-out inventory system to guarantee product freshness and usability.
Superoxide dismutase 1 is an important antioxidant that serves critical and versatile functions within human cells. Therefore, people commonly use its supplements to bolster their natural SOD1 levels, which, in turn, provides the following myriad benefits:
Superoxide dismutase works by scavenging or neutralizing superoxide anions and analogous reactive oxygen species, thus preventing oxidative stress and cellular damage. It, therefore, protects vulnerable brain and skin cells and any other rapidly dividing cell types.
Many SOD products, especially creams, are topical applied to help mitigate wrinkles, age spots, sagging, and other signs of skin aging. By reducing oxidative stress on skin cells, SOD1 helps them stay healthier or perhaps even triggering a rejuvenating effect.
Studies show that SOD can synergistically combine with other antioxidants like vitamin C to boost their effects. So, SOD is present in topical wound dressings and recovery aids to speed up healing by reducing inflammation and oxidative damage. It may also help improve the overall appearance and quality of the repaired tissue.
With its ability to combat oxidative stress throughout the body, SOD1 helps prevent age-related deterioration of cells and tissues. Thus, this slows down the aging process at the cellular level, translating into healthier skin, organ systems, and overall bodily functions well into advanced age.
Oxidative stress is a common denominator of numerous disorders like Alzheimer's disease, Parkinson's disease, other neurodegenerative diseases, and conditions like diabetes and cardiovascular disease. Therefore, exogenous SOD1 supplementation can help ease the disease symptoms and possibly slow down their progression by reducing overall oxidative stress.
Beyond just neutralizing superoxide, SOD1 can reduce the activity of pro-inflammatory pathways. It, therefore, helps with chronic inflammation, usually implicated in various diseases and age-related tissue damage. Hence, SOD1 may provide relief to those with inflammatory conditions such as arthritis and respiratory disorders.
By reducing exercise-induced oxidative stress, SOD1 can enhance endurance, speed up recovery, and potentially improve performance metrics like VO2 max. This makes it appealing to athletes and fitness enthusiasts seeking to minimize the impact of intense training on their bodies.
Generally, SOD1 supplements can work synergistically with other medications and supplements or even improve their effects. But the catch is that users have to consult a healthcare professional before combining them to avoid harmful drug interactions and ensure safe and effective use.
Since SOD is naturally endogenous, it's generally considered safe, especially when taken as directed. Still, some people may experience mild gastrointestinal disturbances or allergic reactions, particularly to exogenous sources like yeast.
The timeframe to witness results from SOD products can also depend on several factors such as the product type, dosage, individual response, and specific health or skin care goals. However, customers usually begin seeing results after several weeks of consistent usage.
The body absorbs superoxide dismutase via advanced encapsulation technologies, such as liposomal delivery systems, which protect the enzyme from degradation in the digestive tract. These technologies also improve the bioavailability of SOD supplements, enabling a larger proportion to reach the bloodstream intact and functional.
Yes, it's safe to apply topical SOD products like lotions and creams daily. However, performing patch tests first for SOD1 sensitivity is always a good idea, and those with sensitive skin should apply it sparingly before increasing frequency.
