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Pure berberine is an extract from several plant roots, bushes, and trees with a yellow hue. These plants include the goldenseal, European barberry, and Oregon grape. The extract has a pharmaceutical look and is sometimes mistaken for a lab-created product. However, it is purely natural and effective for various health problems when used correctly. However, it's good to know that it comes in five main forms, each with strengths and uses. Here's a breakdown of its types.
This form is the most common and often referred to as simply “berberine.” Its reported potency compared to other forms has made it popular among users. In fact, studies show that berberine HCL primarily addresses diabetes and related conditions. Despite its medical feature, practitioners also use berberine HCl as a dietary supplement. This is because it is effective for blood sugar, cholesterol, and blood pressure regulation.
Buyers will mostly find the hydrochloride form packaged alone or as part of blends with compounds like turmeric. The blends commonly seek to address the same conditions as berberine HCl but from different angles, such as improving blood flow.
Berberine sulfate is simply a sodium salt derivative of berberine HCl. It attracts a hefty user base because of its higher water solubility. Berberine sulfate serves the same health purposes as berberine HCl but may be more effective in conditions where higher doses are needed.
Like hydrochloride, berberine sulfate is often sold alone or as part of powder mixtures with other plant extracts. It may also sometimes be encapsulated with other supplements like Magnesium Glycinate for better absorption and synergistic benefits.
Berberine phosphate is less known and wanted than the above two. It is a salt derivative of berberine HCl and berberine sulfate. Its phosphate group makes berberine phosphate more soluble in biological membranes than hydrochloride and sulfate. Affected membranes include cell walls and intestines.
People with diabetes and dyslipidemia may also find this form effective when taken as a supplement. Also worth noting is that berberine phosphate shares the same health benefits as its siblings while being more bioavailable.
Berberine citrate is a salt derivative of berberine and citric acid. Citric acid is a common naturally occurring acid in citrus fruits. Although mostly in the injectable form, vendors pack berberine citrate as an oral supplement with other extracts. It is effective for modulating body sugars, cholesterol levels, weight, and blood pressure.
Berberine citrate has also been shown to promote gut health. So, it can also be used as a stand-alone or auxiliary treatment for irritable bowel syndrome.
This is the last type. It is often in berberine phosphate form. Berberine phosphate is the only form of berberine capable of intravenous delivery.
Pure berberine is a largely single-ingredient supplement. It, therefore, doesn't come with a variety of ingredients as many other supplements do. Its composition is mainly from the roots of the goldenseal plant. However, when blended with other extracts, parts of the other plants may also feature in some blends.
The primary ingredient in pure berberine is berberine itself. It is a yellowisoquinoline alkaloid. As discussed earlier, it is sourced primarily from goldenseal and barberry plants. The berberine compound extracts are usually concentrated in root and stem sections of the source plants.
Some vendors do a further extraction using hydrochloric acid to increase the berberine concentration. Such buyers will then commonly find berberine packaged and branded as berberine HCl. It is known for its ability to regulate body sugars. It can therefore assist diabetes patients and people with weight issues by helping them shed some weight.
While pure berberine is primarily from goldenseal and barberry plants, some vendors include other extracts in the supplement. These are often taken from the same plants.
For example, extracts from barberry's bark and stems are sometimes included. They contain extra compounds like flavonoids. These compounds are known for improving blood circulation and managing cholesterol levels. In some rare cases, vendors extract and include berberine from other plants like Chinese bamboo and tree turmeric. These are less commonly used as they are more challenging to obtain and process.
Berberine is effective when properly processed and used correctly. It functions primarily as a glucose regulator and weight loss agent. This happens because berberine interacts with specific receptors in the body, such as the AMP-activated protein kinase (AMPK) and insulin receptors. By binding to these receptors, berberine mimics insulin. It then enhances glucose uptake in cells while reducing glucose production in the liver.
This leads to improved blood sugar control and lower blood sugar levels. This regulation is particularly beneficial for diabetic patients and anyone with weight issues. Furthermore, when combined with other extracts, berberine improves blood circulation. Better blood flow helps manage cholesterol levels and promote general health.
Buyers in wholesale may also choose to process berberine citrate and other salt derivatives into powder forms. They then package the powders as berberine solely or as a blend with other extracts. When ingested, powders pass to the digestive system, where they are absorbed. From here, the compounds enter the bloodstream and are distributed throughout the body. The compounds interact with various receptors like AMPK and insulin receptors to regulate blood sugar levels
Berberine capsules and tablets are convenient and popular among vendors and end users. In many cases, they contain pure berberine HCl, although they may also have other extracts in personalized medicine. Tablets and capsules are particularly recommended to people with diabetes who need to consistently control their blood sugar levels. The pills are especially effective when taken before or with meals. Noticeable effects may also be felt when the supplements have been taken for extended periods.
When processed into berberine phosphate, pure berberine can be injectable. However, this method should only be done by a qualified medical professional. Intravenous berberine is commonly used in clinical settings to treat diabetic patients and address other health conditions.
Despite being an effective supplement, it has to be taken to the letter for safety and effectiveness. First, diabetic patients currently on medication should consult their doctors before taking pure berberine. Combining it with med may lower blood sugar too much, resulting in hypoglycemia. Health professionals should also be consulted before taking berberine with other supplements. For instance, taking it with turmeric may be dangerous. Turmeric increases berberine absorption, which can cause overdose symptoms.
Pregnant and breastfeeding women should forgo pure berberine too. Although there are no conclusive studies to confirm its effects on babies and fetus, it manages cholesterol levels. Sometimes, it is even blended with fast-acting drugs like insulin. Both of which may affect fetal development or are unsafe for breastfeeding infants.
Berberine should also be avoided by people who are about to go through surgery. The supplement has been reported to interfere with blood clotting. This will increase surgical risks for people who will be undergoing major surgeries.
Despite being rare, berberine users may experience side effects. Common ones include nausea, diarrhea, and stomach cramps, especially when the supplement is first introduced. Most cases settle after a week of use or when the body adjusts. However, people with known sensitivities to new supplements must seek medical advice before taking pure berberine.
Pure berberine doesn't have general endorsements. However, health professionals recommend it for its blood sugar regulation ability. This is particularly important for diabetes patients and people with weight problems. Berberine interacts with certain body receptors to improve insulin sensitivity and glucose uptake. This helps control blood sugar levels effectively.
The plant extract is also beneficial when taken together with other extracts. For example, combining berberine with turmeric can help circulate blood better. This better circulation helps manage cholesterol levels. Professionals also recommend berberine for gut health. Improved gut brings about general health well-being.
Pure berberine is extracted from plants, like goldenseal, and does not have a varying chemical structure. It can't be spoiled or even wears out. However, the effectiveness may reduce over time, particularly with extended exposure to unfavorable storage conditions. Quite similarly, the packaging users put pure berberine in, albeit unlikely, may sometimes get damaged or leak. So, to ensure that pure berberine retains its effectiveness and users get value for money, its storage should follow some guidelines. They include:
Users should store berberine in a cool and dry environment with stable temperatures. Extreme cold can condense moisture, compromising the supplement's effectiveness. On the other hand, extreme heat will degrade the supplement. The capsules may also be damaged, making it hard for users to ingest the supplement.
Vendors may choose to package berberine in airtight jars, bottles, or pouches. These containers and pouches may also have silica gel packets that absorb moisture. This further ensures the supplement's and caps's powder ingredients remain dry and intact. However, vendors must watch the containers' integrity. Damaged jars or leaky pouches reduce berberine's quality. Those using berberine supplements should store it in airtight containers. Leaving it exposed to air will reduce the supplement's effectiveness.
Avoid storing berberine in environments where it will be exposed to sunlight. Also, avoid storing it near strong-smelling substances, such as chemicals and spices. These odors can seep into the container, contaminating the supplement. Exposure to light also degrades the supplement. So, store it in opaque containers or keep it in a cupboard.
Like other supplements, keep pure berberine out of children's and pets' reach. This is to avoid accidental ingestion or poisoning. Furthermore, store it in a sealed container to prevent children from accessing it.
Conversely, parents who buy pure berberine should be keen on the expiry date. The supplement goes through rigorous quality checks before packaging and selling. Nonetheless, there may be exceptions during storage and transportation. So, to ensure the supplement is still safe for ingestion, users should consume it before the expiration date. Always check the expiration date before buying or using pure berberine. Consuming expired supplements can be ineffective and potentially dangerous.
A. Yes, pure berberine can be combined with other supplements. When combined with extracts like turmeric, berberine boosts its effectiveness. This is especially true when targeting diabetes and cardiovascular problems. Pure berberine and turmeric blends are also effective for people suffering high blood sugar, cholesterol, and poor circulation. This is because berberine boosts turmeric's absorption. Occasionally, users may also add magnesium to the mix. This improves blood flow into muscles and reduces hypertension.
A. Yes, pure berberine is effective for multiple diseases. This gives it enough versatility to be used by different people with different diseases. For example, berberine effectively addresses diabetes and high cholesterol simultaneously. However, it works best when combined with other extracts like turmeric. Therefore, barbers resellers targeting diabetic and cardiovascular customers bulk buy pure berberine. They often sweeten the deal by adding other extracts like turmeric when repackaging the supplement.
A. Users can boost pure berberine effectiveness by taking it with food. The supplement is better absorbed when taken with meals that contain carbohydrates. This is because combining food and berberine favors its interaction with insulin. Taking the supplement with high-carb meals maximizes its potential, enhancing glucose uptake and regulating blood sugar.
A. Users should wait for at least three hours before taking the next dose. However, this timeframe may differ depending on the dosage and the user’s medical state. most people will take several caps or tablets daily and spread the intake evenly throughout the day. For instance, if the daily intake is four caps, users will take one cap every three hours.
A. No, consuming expired berberine or any other supplement is dangerous and ineffective. This also applies to medicines and drugs. Usually, manufacturing companies set expiration dates after performing tests to ensure product potency. Consuming expired products exposes users to ineffective; dangerous chemicals may have degraded into harmful substances.
A. Taking expired berberine lowers its effectiveness. This means instead of controlling blood sugar and cholesterol as it should, berberine may leave users exposed to the conditions. Unfortunately, it may also cause nausea, diarrhea, vomiting, and stomach cramps. This is because the degraded chemicals may be rough on the digestive tract.
