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Market Overview: The pharmaceutical multi mill machine market is poised for considerable growth, paralleling advancements in pharmaceutical manufacturing technologies. As of 2023, the broader pharmaceutical equipment market, which includes multi mills, was valued at approximately USD 33.3 million, with projections indicating it could reach USD 44.8 million by 2030, reflecting a CAGR of 4.3%, according to Global Industry Analysts. This growth trajectory is supported by innovations in production processes, including the rise of 3D printing technologies, which enhance the precision and efficiency of drug manufacturing. The U.S. market alone was estimated at USD 8.8 million in 2023, with China expected to achieve a robust growth rate of 6.5% CAGR, emphasizing the regional dynamism in the pharmaceutical machinery sector.
Industry Insights: Consumer behavior in the pharmaceutical sector is shifting towards more personalized and efficient production methods, driving the demand for pharmaceutical multi mill machines. As companies increasingly adopt advanced manufacturing technologies, the need for versatile milling solutions has become apparent. The Twin Screw Extruders segment, for instance, is projected to grow significantly, indicating a broader trend toward multi-functional equipment that can handle diverse materials and processes. Additionally, companies face challenges such as regulatory compliance and the need for sustainable practices, pushing them to innovate continually. The market is also witnessing a rise in niche segments focusing on customized drug delivery systems, aligning with the overall trend toward personalized medicine. This evolving landscape presents numerous opportunities for stakeholders in the pharmaceutical machinery market.
Pharmaceutical multi mill machines are available in different types to meet specific processing needs. Here are some of the popular ones:
Multi-directional mill:
The three/ multi-directional milling is a tabletop, potent, and compact instrument that clocks at three different speeds. It has been intended to provide homogeneity of all types of crystallized products accordingly, which will produce small-sized end products. This type of multi-mill has a process chamber with an effective diameter of 6.5 cm and a height of 41.5 cm. Its processing capacity can reach 5-20 kg per hour, depending on the material's properties and the mill's operating parameters.
Multi-directional oscillating mill:
This oscillating milling machine is designed for heavy-duty tasks and comes in an O-Os3/4 variant. It operates by oscillating the process chamber in a horizontal plane at a fixed speed and simultaneously moving the material vertically by an eccentric screw. This type of pharmaceutical multi mills has an effective diameter of 28.5 cm and a height of 72.5 cm. Its processing capacity can reach 20-80 kg per hour.
Multi-directional high-capacity mill:
It has a higher height and capacity than oscillating mills. This type is more efficient and processes more materials in less time. Its processing capacity can reach 100-500 kg per hour, making it suitable for large-scale production. Moreover, this kind of oscillating multi-mill also has an H-Os5/8 variant. Its effective diameter is 38 cm and height is 73.5 cm.
Multi-directional super-high capacity mill:
The super-high-capacity oscillating milling machine is ideal for enormous milling tasks in the pharmaceutical sector. It is the most prominent model and offers the highest processing capacity. Its processing capacity can reach 1,000-2,000 kg per hour. In addition, it also has an S-Os6/3 variant. Its effective diameter is 51 cm, and its height is 68 cm.
Swing hammer milling machine:
Swing hammer milling machines are versatile and widely used in the pharmaceutical industry to crush and sieve materials. These machines incorporate replacement hammers in varied assortments and styles to increase the machines' adaptability. Moreover, these milling machines also have different series to choose from, for instance, HM-Os6 series. Its effective diameter is 18.5 cm, and its height is 52 cm. Its processing capacity can reach 30-150 kg per hour.
Production capacity
Depending on the factors like electric motor horsepower and product nature. They can vary greatly; however, it is usually hundred kilograms to over a thousand kilograms each hour.
Motor power
The motor power of a multi milling machine varies based on the model and is classified in terms of kw/hp. For example, one model might have a power of 5.5kw/7.5hp.
The range of milling sizes
It can be a fine particle size of 0.1-2mm, a very coarse size of up to 10mm, or even larger, depending on the configuration and type of screens used.
The nature of the milling process
Some machines can handle wet products and oils and dry ones like powders and granules. Certain types of teeth cutters are used for wet ones, while screens are preferred for dry ones.
It is crucial to keep the pharmaceutical multi mill machine up to standard so as to achieve its functional capacity. The following parts may require special attention:
Maintenance of the electric motor:
Daily inspection for vibrations, overheating, noise, or any signs of unusual operation. Lubricate working parts as instructed. Ensure electric supply is of the required voltage to avoid under-performance and over-heating. Engage a qualified technician to service the motor periodically in accordance with the manual.
Maintenance of the gear transmission system:
Maintain proper and sufficient lubrication of gears and chains so that there is no wear and tear, noise, slippage, or overheating. Inspect often and replace lubricants per instructions.
Maintenance of the pulverizing parts:
The blades need frequent inspections and sharpenings or replacements. Screens used to filter the desired product size also need to be free from blockages and tears or wear. Clean them thoroughly after use.
Clean the machine:
After each day’s use, or at least weekly, clean the machine thoroughly to avoid product buildup, which can affect its milling efficiency and even product quality. Use appropriate tools and cleaning agents, followed by thorough rinsing and drying. Dispose of waste as per guidelines.
The pharmaceutical multi mill machine has many usage scenarios in many industries. Some of them are:
Food industry:
A multi-mill can grind food items such as grains, sugar, tea, coffee, fruits, nuts, and vegetables into fine or coarse particles. The food industry uses it to make cooking easier and improve the quality of farm produce.
Veterinary medicines:
Multi-mills are used to manufacture veterinary medicines and medicines for children. Instead of using harmful additives and drugs, most farm owners will prefer drugs their farm produce can take instead of pharmaceuticals made for humans. Vet Pharmaceutics Industries use multi-mills to create medicines for farm animals.
Cosmetics industry:
Cosmetics industries use multi-mills to grind a variety of extracts, fillers, minerals, and active components. The goal is to improve formulation and absorption. Furthermore, a majority of cosmetics contain herbal extracts. Therefore, herbal industries may use a multi-mill to obtain the required fine particle size before preparing the herbal extract.
Chemical industry:
Chemical processing plants use pharmaceutical multi-mill machines for chemical and dye milling, pulverization of chemicals, grinding of pigments, processing of powder coatings, and reduction in size of polymers and plastics. Industries that produce chemicals, coatings, dyes, and pigments will use a chemical multi-mill machine to reduce larger particles to smaller ones. This action improves solubility, dispersibility, and reactivity, as well as enhances the product's quality, performance, and stability.
Material recycling:
Multi-mills are used in the production of recycled materials to grind and pulverize plastic, rubber, or paper waste, enabling recycling and the creation of new materials. Pharmaceutical machines with multi-mills are useful for recycling pharmaceutical production waste (such as excess tablets and capsules) to minimize waste and enhance resource use.
Business buyers shopping for a multi pharma mill should check some technical and safety features.
Flexible milling:
A key feature for a multi-pharma mill is the machine's capacity to mill products with varying hardness levels, such as dry and wet substances. MP-90 Multi mills, for example, can efficiently crush both hard and soft materials, dry and moist, due to their diverse operational modes.
Multiple-milling tools:
Another salient feature to consider is the availability of various milling devices for diverse milling procedures. According to the manufacturers' manual, pharmaceutical multi-mill machines like the MP-90 have varied types of sieves that can produce granules in different sizes. For instance, a sieve with an aperture of 0.5 mm will produce finer granules than one with an aperture of 2 mm.
Milling consistency:
A multi-mill's capacity to maintain a steady granule size is also crucial. This device has sieves with various openings. The type utilized will determine the result. Even when varied sieves are utilized, the sieve's blocking and unblocking process is almost the same. As a result, operators may quickly and consistently maintain the sieve, ensuring that uniform granule size distribution is attained.
Simple operation:
Most employers desire machines operated with minimal training and simplified maintenance. Choose a machine powered by AC/DC motors with digital touch-screen controls. Such a machine will have simple, automatic, useful, and easy-to-operate milling, granulating, pulverizing, and sieving functions.
User manual:
Simple operation also means a documented procedure. A clear and concise manual document is vital for setting the device up, operating it, and shutting it down safely. The manual needs to include a parts diagram, troubleshooting guide, and maintenance schedule.
Emergency safeguards:
Multi-mills have various operational modes. Safety features like emergency stop buttons are crucial for users' safety. The users may be milling, sieving, or grinding at the time. A quick emergency stop is needed when safety requires it. The emergency button provides a quick device pause without going into the milling process or production line. Operators can manually halt the operating device with the emergency switch instead of waiting for the set time to elapse.
Q1: How does a Multi Mill work?
A1: The multi-mill functions in a simple way. In this apparatus, the material to be milled is put in the container or hopper. The vibration of the machine and the reamer or cylinder's rotation causes the material to be milled and fall down through the screen.
Q2: What are the benefits of a multi-mill in the pharmaceutical industry?
A2: The Multi Mill offers numerous benefits like milling, mixing, sieving, granulation, dispersing, and emulsifying various products. The machine can process a wide array of solid and liquid products with differing viscosities. It is also uncomplicated to operate, reducing the need for extensive training and technical expertise. Cleaning and maintaining the device are equally straightforward, which aids in upholding industry compliance standards.
Q3: Is a multi-mill used only in pharma industries?
A3: The multi-mill is not just limited to the pharmaceutical industry. It's a versatile machine used in food, chemical, cosmetics, and other industries.
Q4: Which types of powders fall under the scope of pharmaceutical milling?
A4: In the pharmaceutical industry, milling is typically used to handle air-classified powders, such as lactose, titanium dioxide, fine calcium carbonate, spray-dried active ingredients, and any other chemical for which milling is required to achieve the proper particle size distribution.
