Empty plastic capsules

Types of empty plastic capsules

Empty plastic capsules are available in various types, which include the following:

• Gelatin capsules

  Gelatin capsules are the most popular kind of empty plastic capsules. They are made from hydrolyzed animal gelatin, water, and glycerin. These empty capsules are biodegradable and dissolve quickly, making them ideal for various applications. They are available in several sizes, ranging from tiny size 000 to large size 4, to accommodate different amounts of filling. Normally, size 000 is the largest and can hold about 1,500 mg of material, while size 4 is the smallest and can hold approximately 400 mg of material. These gelatin capsules are widely used in the pharmaceutical and nutraceutical industries to hold dietary supplements, vitamins, and medications. Additionally, their clear and opaque versions offer aesthetic choices for consumers.

• Vegetable capsules

  Vegetable capsules are also known as plant-based or HPMC (hydroxypropyl methylcellulose) capsules. They are manufactured from plant-derived polysaccharides, usually from pine or tapioca. These empty plastic capsules are suitable for vegans and vegetarians and are a great choice for people who have food allergies or restrictions. Similar to gelatin capsules, vegetable capsules come in many sizes and can hold the same quantity of material. They are more stable under high humidity and can dissolve in the body without the use of animal products. Normally, these empty plastic capsules are used to encapsulate various substances, particularly those that require a vegetarian or vegan-friendly delivery system.

• Colored capsules

  These empty plastic capsules come in different colors, ranging from red to blue, pink to green. Their coloring can be solid, translucent, or opaque. The coloring is usually done using food-grade dyes that are safe to use. They are available in both gelatin and vegetable capsules. These colored capsules serve both practical and aesthetic purposes. They make it easy to differentiate between various formulations or dosages. Additionally, the color can make the capsules more appealing to consumers. Their popularity is on the rise in the dietary supplement market, where companies try to make their products stand out. The colors used in the capsules can be mixed to create a variety of hues.

• Capsule-in-a-capsule

  Capsule-in-a-capsule is a two-part system that contains a smaller capsule within a larger one. The smaller inner capsule can hold a different formulation that is difficult to mix or a liquid filling. These capsules offer a unique delivery system that is flexible and convenient. They allow for the separate delivery of two different substances, which can be combined at the time of ingestion. This type of empty capsule is useful for products that need to be taken together but have ingredients that are incompatible when mixed.

How to choose empty plastic capsules

Choosing the right empty plastic capsules is important for ensuring effective and patient-friendly drug delivery. Here are some tips to consider when selecting empty plastic capsules:

• Size and Volume

  Capsules come in different sizes (ranging from smallest size 5 to largest size 000), so choose the one that fits the dose. Larger sizes hold more contents, while smaller sizes are ideal for lower doses. The size of the capsule should be determined by the volume of the fill material and the required dosage.

• Material

  Plastic or synthetic capsules are more durable and resistant to moisture than gelatin capsules. However, the choice between vegetarian-based HPMC capsules and gelatin capsules depends on dietary restrictions, preferences, and the nature of the fill material. HPMC capsules are suitable for vegetarians and those with religious restrictions, while gelatin capsules are more affordable and stronger.

• pH Sensitivity

  Some materials require enteric-coated capsules for delayed release until they reach the intestines. Enteric coating protects the capsule from dissolving in acidic environments and ensures the contents are released at a specific site in the gastrointestinal tract.

• Color and Opacity

  Available in a range of colors, opaque capsules provide more light protection, while clear capsules allow visibility of the fill material. Choose based on aesthetic preferences and light sensitivity of the material.

• Compatibility

  Ensure the capsule material is compatible with the fill material to avoid chemical interactions that might affect stability or efficacy.

• Manufacturing Standards

  Choose capsules manufactured under good manufacturing practices to ensure quality, safety, and consistency.

• Supplier Reputation

  Buy from reputable suppliers with positive reviews to ensure one gets quality empty plastic capsules and good customer service.

Functions, features, and design of empty plastic capsules

Function

• Drug Delivery

  Empty plastic capsules are primarily used for the delivery of drugs. They offer a convenient and accurate way to administer pre-measured doses of powdered or liquid substances.

• Masking Taste or Odor

  Plastic capsules can effectively mask the unpleasant taste or odor of the ingredients encapsulated. This makes them ideal for use with dietary supplements and medications that have an unpalatable flavor.

• Improving Bioavailability

  Some formulations can have their bioavailability improved when they are enclosed in capsules. This is because the capsules can protect the contents from degradation until they reach the appropriate area in the digestive system.

Features

• Customizable Sizes

  Empty plastic capsules come in a variety of sizes that range from small to large. This makes it possible to choose a suitable size depending on the required dosage.

• Color and Opacity Options

  Plastic capsules can be available in many different colors, which can be solid, transparent, or translucent. The different colors allow for easy identification and differentiation of various formulations.

• Interlocking Mechanism

  Many empty plastic capsules feature an interlocking mechanism that ensures the two halves of the capsule stay securely joined. This prevents leakage or spillage during handling.

Design

• Smooth Surface

  Smooth surfaces are easier to fill and clean. The surfaces also reduce friction and prevent the contents from adhering to the capsule walls.

• Sealing Options

  Some capsules come with additional sealing options like banding or locking systems, which provide extra security to the contents and deter tampering.

• Degassing Features

  The design of some capsules includes features for degassing, which allow gases to escape from the filled capsule. This prevents pressure buildup and potential leakage.

Safety and quality of empty plastic capsules

Safety and quality are crucial factors when considering empty plastic capsules. They ensure the well-being of the individual consuming the medication and the efficacy of the drug delivery system.

• Material safety

  Manufacturers make plastic capsules from non-toxic, biocompatible materials, such as Polyvinyl Alcohol. This guarantees that no harmful substances leach into the medicine filled in the capsules. The materials also undergo thorough testing to ensure they do not cause any adverse reactions when they come into contact with the body.

• Quality standards

  Empty plastic capsules come with high-quality standards compliance. Various organizations, including the International Organization for Standardization (ISO) and the United States Pharmacopeia (USP), set these standards. These organizations ensure that capsules meet safety, quality, and efficacy requirements.

• Integrity and durability

  Empty plastic capsules undergo rigorous integrity testing to ensure their durability and strength. These tests check their resistance to factors like pressure, heat, and humidity. The tests also ensure that the capsules do not break or dissolve prematurely, hence delivering the medication as needed.

• Manufacturing processes

  The manufacturing of empty plastic capsules takes place in cleanroom environments. These environments aim to reduce the risk of contamination. In addition, the processes follow strict quality control measures to ensure the capsules meet the required safety and quality standards. The measures include regular inspections and testing at different production stages.

• Consumer safety

  Regulatory bodies ensure that empty plastic capsules are safe for consumer use. They also provide guidelines on their proper use and handling. This ensures that consumers are well-informed about the safety of these capsules.

Q&A

Q1: What are empty plastic capsules made of?

A1: Empty plastic capsules, also known as gelatin or HPMC capsules, are typically made of either animal-derived gelatin or plant-derived materials such as hydroxypropyl methylcellulose (HPMC).

Q2: How long can empty plastic capsules last?

A2: Empty plastic capsules can last up to two years if stored in a cool, dry place away from direct sunlight and humidity.

Q3: Can empty plastic capsules be reused?

A3: It is not advisable to reuse empty plastic capsules. Reusing them can compromise the integrity and safety of the capsules.

Q4: What colors are available for empty plastic capsules?

A4: Empty plastic capsules are available in various colors, commonly a combination of red, blue, green, yellow, and purple.

Q5: Are empty plastic capsules vegan?

A5: Yes, some empty plastic capsules are vegan. They are made from plant-derived materials such as cellulose.